The broader cognitive phenotype of autism in parents:: how specific is the tendency for local processing and executive dysfunction?
The broader cognitive phenotype of autism in parents:: how specific is the tendency for local processing and executive dysfunction?
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DOI：
10.1111/j.1469-7610.2006.01603.x
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发表时间：
2006-06-01
影响因子：
7.6
通讯作者：
Poustka, Fritz
中科院分区：
文献类型：
--
作者：
Boelte, Sven;Poustka, Fritz
背景资料：本研究的目的是调查与早发性精神分裂症（EOS）和精神发育迟滞（MR）个体的父母相比，自闭症谱系障碍（ASD）受试者的父母的局部处理风格（“弱中央一致性”）和执行功能障碍的趋势。方法：对62例ASD患者的父母、36例EOS患者的父母和30例MR患者的父母进行检查。两个尺度上的数据表明当地的视觉处理（嵌入图形测试，块设计）和三个执行功能测试（威斯康星州卡片分类测试，河内塔，Trailmaking测试）收集所有参与者。结果：与对照组相比，ASD受试者的父母在嵌入图形测试中的表现明显更快。未观察到其他实质性组间差异。结论：研究结果表明，在视觉脱嵌方面，局部处理的趋势增加可能是父母中自闭症更广泛的认知表型的一个相对特定的核心特征。
Background: The objective of this study was to investigate the tendency for local processing style ('weak central coherence') and executive dysfunction in parents of subjects with an autism spectrum disorder (ASD) compared with parents of individuals with early onset schizophrenia (EOS) and mental retardation (MR). Method: Sixty-two parents of subjects with ASD, 36 parents of subjects with EOS and 30 parents of subjects with MR were examined. Data on two scales indicative of local visual processing (Embedded Figures Test, Block Design) and on three executive function tests ( Wisconsin Card Sorting Test, Tower of Hanoi, Trailmaking Test) were collected for all participants. Results: Parents of subjects with ASD performed significantly faster on the Embedded Figures Test compared with both control samples. No other substantial group differences were observed. Conclusions: The findings indicate that an increased tendency for local processing in terms of visual disembedding could be a relatively specific core feature of the broader cognitive phenotype of autism in parents.