Hemoglobin levels and 30-day mortality in patients after myocardial infarction
Hemoglobin levels and 30-day mortality in patients after myocardial infarction
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DOI：
10.1016/j.ijcard.2004.10.043
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发表时间：
2005-04-20
影响因子：
3.5
通讯作者：
Zijlstra, F
中科院分区：
文献类型：
--
作者：
Lipsic, E;van der Horst, ICC;Zijlstra, F
Background: Anemia is an independent risk factor for cardiovascular (CV) outcomes in patients with coronary artery disease and heart failure. However, the effect of hemoglobin levels on short-term CV mortality in patients with acute myocardial infarction (MI) remains unclear.Methods: In a retrospective study we analyzed 1841 consecutive patients admitted with the diagnosis of acute MI. The primary end-point of the study was 30-day mortality. Patients were categorized according to the hemoglobin level on admission (10 g/dl or less, or greater than 10 g/dl).Results: The overall 30-day mortality was 10.3%. The mortality was 21.6% in patients with hemoglobin levels on admission 10 g/dl (p < 0.001). Multivariate logistic regression analysis showed, that lower hemoglobin concentration is an independent predictor of 30-day mortality, when adjusted for other risk factors (HR 1.76, CI 1.08-2.85; p = 0.02).Conclusions: Lower levels of hemoglobin are associated with higher short-term mortality in patients with acute MI. Specific therapeutic strategies in anemic patients with MI should be further considered. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
