Ultrasound lung comets for the differential diagnosis of acute cardiogenic dyspnoea: A comparison with natriuretic peptides
Ultrasound lung comets for the differential diagnosis of acute cardiogenic dyspnoea: A comparison with natriuretic peptides
复制标题
DOI：
10.1016/j.ejheart.2007.10.009
复制
发表时间：
2008-01-01
影响因子：
18.2
通讯作者：
Picano, E.
中科院分区：
文献类型：
--
作者：
Gargani, L.;Frassi, F.;Picano, E.
背景：以急性呼吸困难为主要表现的呼吸困难是医生经常面临的诊断难题。主要鉴别诊断为心源性呼吸困难和非心源性呼吸困难。利钠肽已被证明在这种情况下是有用的。超声肺彗星(ULCs)是一种简单的、可用于评估肺充血的超声方法。目的：与利钠肽比较，评价ULCs预测心源性呼吸困难的准确性。胸部超声和NT-proBNP评估最长相隔4h，并独立分析。通过放置在前胸和侧胸的心脏探头来评估ULCs。两名独立医生对ULCS和NT proBNP结果视而不见，查阅了所有病历，以建立呼吸困难的病因学诊断。结果：122名患者被证实患有心源性呼吸困难，27名患者被排除。ULCs数与NT-proBNP值呈显著正相关(r=0.69，p
Background: Acute dyspnoea as a presenting symptom is a frequent diagnostic challenge for physicians. The main differential diagnosis is between dyspnoea of cardiac and non-cardiac origin. Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method which can be used to assess pulmonary congestion.Aim: To evaluate the accuracy of ULCs for predicting dyspnoea of cardiac origin compared to natriuretic peptides.Methods: We evaluated 149 patients admitted with acute dyspnoea. Chest sonography and NT-proBNP assessments were performed a maximum of 4 h apart and independently analyzed. ULCs were evaluated via cardiac probes placed on the anterior and lateral chest. Two independent physicians, blinded to ULCs and NT proBNP findings, reviewed all the medical records to establish the aetiologic diagnosis of dyspnoea.Results: Cardiogenic dyspnoea was confirmed in 122 patients and ruled-out in 27 patients. The number of ULCs was significantly correlated to NT-proBNP values (r=.69, p