Adverse reactions to smallpox vaccine: The Israel Defense Force experience, 1991 to 1996. A comparison with previous surveys
Adverse reactions to smallpox vaccine: The Israel Defense Force experience, 1991 to 1996. A comparison with previous surveys
复制标题
DOI：
10.1093/milmed/165.4.287
复制
发表时间：
2000-04-01
影响因子：
1.2
通讯作者：
Shemer, J
中科院分区：
文献类型：
--
作者：
Haim, M;Gdalevich, M;Shemer, J
本研究的目的是评估1991年至1996年招募的以色列国防军新兵队列中天花疫苗接种后并发症的发生率，并将其与20世纪60年代大型调查中类似年龄组的报告率进行比较。总体并发症发生率为每万名接种者0.4例，严重并发症发生率非常低，与此前公布的数据相似。我们的结论是，在年轻健康的成年人中，接种天花疫苗是相对安全的，并发症的发生率较低。在我们的研究中，这个年龄组的严重并发症非常罕见。然而，并发症发生率随着初次接种者百分比的增加而增加。
The aim of the present study was to assess the post-smallpox vaccination complication rate in a cohort of Israel Defense Force recruits enlisted in the calendar years 1991 to 1996 and to compare it with rates reported, in similar age groups, in large surveys during the 1960s. The overall complication rate was 0.4 per 10,000 vaccinees, and the rate of severe complications was very low, similar to previously published data. We conclude that among young healthy adults, vaccination with smallpox vaccine is relatively safe and is associated with a low rate of complications. Severe complications were very rare in this age group in our study. However, the complication rate is increasing with the increased percentage of primary vaccinees.