Prescription Opioid Misuse and Sports-Related Concussion Among High School Students in the United States.
Prescription Opioid Misuse and Sports-Related Concussion Among High School Students in the United States.
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DOI：
10.1097/htr.0000000000000706
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发表时间：
2021-09-01
期刊：
影响因子：
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通讯作者：
Groenewald CB
中科院分区：
文献类型：
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作者：
Tham SW;Palermo TM;Chrisman SPD;Groenewald CB
脑震荡在青少年中非常普遍，并且与较高的药物使用风险相关。随着青少年使用阿片类药物的增加，一种值得关注的物质使用形式是滥用处方阿片类药物。本研究旨在探讨美国高中生过去一年的运动相关脑震荡史与当前处方阿片类药物滥用之间的关联。 2019 年青少年危险行为调查的二次数据分析。具有全国代表性的高中生样本 (n = 7,314)。横断面研究 参与者被问及在过去 12 个月内是否经历过与运动或体力活动相关的脑震荡；以及他们在过去 30 天内是否滥用任何处方阿片类药物。在该队列中，14.0% 的人报告在过去 12 个月内遭受过脑震荡，6% 的人报告目前滥用处方阿片类药物。与无脑震荡史的患者 (5.5%，p = 0.0015) 相比，有脑震荡史的患者 (9.9%) 处方阿片类药物滥用发生率更高。控制协变量（性别、种族/族裔、其他物质使用、抑郁症状）后，患有脑震荡的青少年滥用处方阿片类药物的几率是没有脑震荡的青少年的 1.5 倍（调整后比值比 [OR] = 1.5；95% 置信区间 1.0、2.3；p = 0.029）。即使考虑到抑郁症状和其他物质使用，脑震荡也与美国年轻人滥用处方阿片类药物有关。需要进行纵向研究来测试因果关系并了解青少年脑震荡和阿片类药物滥用之间关联的生物行为机制。
Concussion is highly prevalent in adolescents and associated with a higher risk of substance use. With the rising use of opioids among adolescents, one form of substance use of concern is misuse of prescription opioids. This study aimed to examine the association between history of sports-related concussion in the past year and current prescription opioid misuse among high school students in the United States (US). Secondary data analysis from the 2019 Youth Risk Behavior Survey. Nationally representative sample of high school students (n = 7,314). Cross-sectional study Participants were asked whether they experienced any concussions related to sports or being physically active during the past 12 months; and whether they had any prescription opioid misuse within the past 30 days. Amongst this cohort, 14.0% reported sustaining a concussion in the past 12 months and 6% reported current prescription opioid misuse. Prevalence of prescription opioid misuse was higher among those with history of concussion (9.9%) compared to those without concussion (5.5%, p = 0.0015). Controlling for covariates (sex, race/ethnicity, other substance use, depressive symptoms), the odds of prescription opioid misuse was 1.5 times higher for adolescents with concussion compared to those without (adjusted odds ratios [OR] = 1.5; 95% confidence interval 1.0, 2.3; p = 0.029). Concussion was associated with prescription opioid misuse among US youth, even after accounting for depressive symptoms and other substance use. Longitudinal studies are needed to test causal relationships and understand biobehavioral mechanisms that underlie associations between concussion and opioid misuse in adolescents.