Growth hormone: independent release of big and small forms from rat pituitary in vitro.
Growth hormone: independent release of big and small forms from rat pituitary in vitro.
复制标题
生长激素：体外大鼠垂体独立释放的大小形式。
DOI：
10.1126/science.1111113
复制
发表时间：
1975
期刊：
影响因子：
56.9
通讯作者：
L. Frohman
中科院分区：
文献类型：
--
作者：
M. Stachura;L. Frohman
免疫沉淀法已证实灌流的大鼠垂体顺序释放大形式和小形式的生长激素。 The results suggest that either the two forms are independently synthesized and released, or that a newly synthesized molecule of big growth hormone follows one of two paths: direct release or intracellular processing through the storage compartment with conversion to small growth hormone.
Sequential release of big and small forms of growth hormone by perifused rat pituitaries has been demonstrated by immunoprecipitation. The results suggest that either the two forms are independently synthesized and released, or that a newly synthesized molecule of big growth hormone follows one of two paths: direct release or intracellular processing through the storage compartment with conversion to small growth hormone.