Intimate combination of low- and high-resolution image data: I. Real-space PET and (1)H(2)O MRI, PETAMRI.
Intimate combination of low- and high-resolution image data: I. Real-space PET and (1)H(2)O MRI, PETAMRI.
复制标题
低分辨率和高分辨率图像数据的紧密结合:I. 实空间 PET 和 (1)H(2)O MRI、PETAMRI。
DOI:
10.1002/(sici)1522-2594(199908)42:2
复制
发表时间:
1999
影响因子:
3.3
通讯作者:
SpringerJr,CS
中科院分区:
文献类型:
--
作者:
Sammi,MK;Felder,CA;Fowler,JS;Lee,JH;Levy,AV;Li,X;Logan,J;Pályka,I;Rooney,WD;Volkow,ND;Wang,GJ;SpringerJr,CS
Two different types of (co‐registered) images of the same slice of tissue will generally have different spatial resolutions. The judicious pixel‐by‐pixel combination of their data can be accomplished to yield a single image exhibiting properties of both. Here, axial18FDG PET and1H2O MR images of the human brain are used as the low‐ and high‐resolution members of the pair. A color scale is necessary in order to provide for separate intensity parameters from the two image types. However, not all color scales can accommodate this separability. The HSV color model allows one to choose a color scale in which the intensity of the low‐resolution image type is coded ashue, while that of the high‐resolution type is coded asvalue, a reasonably independent parameter. Furthermore, the high‐resolution image must have high contrast and be quantitative in the same sense as the low‐resolution image almost always is. Here, relaxographic MR images (naturally segmented quantitative1H2O spin‐density components) are used. Their essentially complete contrast serves to effect an apparent editing function when encoded as the value of the color scale. Thus, the combination of18FDG PET images with gray‐matter (GM) relaxographic1H2O images produces visually “GM‐edited”18FDG PETAMR (positron emission tomography and magnetic resonance) images. These exhibit the high sensitivity to tracer amounts characteristic of PET along with the high spatial resolution of1H2O MRI. At the same time, however, they retain the complete quantitative measures of each of their basis images. Magn Reson Med 42:345–360, 1999. Published 1999 Wiley‐Liss, Inc.