An unusual syndrome of a devastating noninflammatory vasculopathy associated with anticardiolipin antibodies: report of two cases.

An unusual syndrome of a devastating noninflammatory vasculopathy associated with anticardiolipin antibodies: report of two cases.
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与抗心磷脂抗体相关的破坏性非炎症性血管病的不寻常综合征:两例报告。

DOI:
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发表时间:
1987
影响因子:
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通讯作者:
Robert M. Bennett
Robert M. Bennett
中科院分区:
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文献类型:
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作者:
Shirley B. Ingram;S. Goodnight;Robert M. Bennett

文献摘要

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我们描述了2例抗心磷脂抗体显著升高的患者,他们发生了以非炎症性血管病变为特征的多器官疾病。他们的病例值得注意的是他们的血栓素质的暴发性,这是由四肢突出的网状活体所预示的。两名患者都有血清学特征和唾液腺活检结果,这与原发性干燥综合征的诊断一致。
We describe 2 patients with marked elevations of anticardiolipin antibodies who developed multiple-organ disease characterized by a noninflammatory vasculopathy. Their cases were remarkable for the fulminant nature of their thrombotic diathesis, which was heralded by a prominent livedo reticularis of the extremities. Both patients had a serologic profile and salivary gland biopsy findings that were consistent with a diagnosis of primary Sjögren's syndrome.