Controllable gas/liquid/liquid double emulsions in a dual-coaxial microfluidic device.
Controllable gas/liquid/liquid double emulsions in a dual-coaxial microfluidic device.
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DOI：
10.1039/c2lc21193a
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发表时间：
2012-05
期刊：
影响因子：
6.1
通讯作者：
Jian-hong Xu;Ran Chen;Yundong Wang;G. Luo
中科院分区：
文献类型：
--
作者：
Jian-hong Xu;Ran Chen;Yundong Wang;G. Luo
本文提出了一种简单而新颖的方法，在同一个双同轴微流控装置中制备单分散的气/油/水（G/O/W）和气/水/油（G/W/O）双重乳液。系统地研究了三相流速对微泡、液滴尺寸和微泡包封数的影响。通过连续调节流量，在相同的几何构型下成功合成了两种不同类型的具有不同内部结构的气/液/液（G/L/L）复乳。建立了预测双乳液尺寸和结构的数学模型。这种简单的方法为以微泡为模板制备中空多孔微球提供了一种新的思路。
This article presents a simple and novel approach to prepare monodispersed gas-in-oil-in-water (G/O/W) and gas-in-water-in-oil (G/W/O) double-emulsions in the same dual-coaxial microfluidic device. The effects of three phase flow rates on the sizes of microbubbles and droplets and the number of the encapsulated microbubbles were systematically studied. We successfully synthesized two different types of gas/liquid/liquid (G/L/L) double emulsions with different inner structures in the same geometry by adjusting the flow rates sequentially. Mathematical models were developed to predict the size and structures of the double emulsions. This simple approach gives a new idea for preparing hollow and porous microspheres with microbubbles as the direct core/pores templates.