CELLULAR INTERSTITIAL PNEUMONITIS IN INFANTS - A CLINICOPATHOLOGICAL STUDY
CELLULAR INTERSTITIAL PNEUMONITIS IN INFANTS - A CLINICOPATHOLOGICAL STUDY
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DOI：
10.1378/chest.101.4.1065
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发表时间：
1992-04-01
期刊：
影响因子：
9.6
通讯作者：
MARK, EJ
中科院分区：
文献类型：
--
作者：
SCHROEDER, SA;SHANNON, DC;MARK, EJ
5名婴儿有间质性肺炎，组织学检查结果不变，这与以前描述的儿童不同。 所有的婴儿在出生时都表现为呼吸急促，尽管进行了治疗，但在临床上和放射学上都表现为持续性疾病。 在每例病例中，开放性肺活检显示由于苍白的卵圆形和梭形组织细胞而导致的弥漫性间质增厚，无瘢痕形成。 这种新生儿细胞性间质性肺炎在临床和组织学上均不同于成人和儿童常见的间质性肺炎、淋巴细胞性间质性肺炎和脱屑性间质性肺炎。 这种新生儿细胞性间质性肺炎的病因尚不清楚。
Five infants had interstitial pneumonitis with constant histologic findings, which was different from that previously described in children. All the infants presented with tachypnea at birth and persistent disease, both clinically and radiographically, despite treatment. Open-lung biopsy in each case showed a diffuse interstitial thickening due to pale oval and spindle-shaped histiocytes without scarring. This neonatal cellular interstitial pneumonitis differs both clinically and histologically from the usual interstitial pneumonitis, lymphocytic interstitial pneumonitis and desquamative interstitial pneumonitis observed in adults and children. The etiology of this cellular interstitial pneumonitis in neonates is unknown.