Familial benign chronic pemphigus: the role of pyogenic bacteria.
Familial benign chronic pemphigus: the role of pyogenic bacteria.
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家族性良性慢性天疱疮：化脓性细菌的作用。
DOI：
10.1001/archderm.1959.01560210060011
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发表时间：
1959
影响因子：
--
通讯作者：
L. Loewenthal
中科院分区：
文献类型：
--
作者：
L. Loewenthal
皮肤化脓性感染在家族性良性慢性天疱疮 (FBCP) 病变的发生中起重要作用，这一信念源于一些偶然的观察结果，并得到实验证据的证实。我建议首先说明得出这一结论的步骤，并将对先前文献的讨论留到本文的后面部分。病例报告 病例 1——一名 56 岁的白人女性，首次就诊于 1951 年 7 月 27 日。自 17 岁起，复发性水疱和大疱性病变累及腋窝，偶尔累及颈部两侧。袭击往往发生在冬末（即南非的七月至九月）并持续约六周。自由的时间间隔从几个月到几年不等。过去，几次暴露于伦琴射线总是
The belief that cutaneous infection with pyogens plays an important part in the genesis of lesions of familial benign chronic pemphigus (FBCP) arose from a few chance observations and has been strengthened by experimental evidence. I propose beginning with an account of the steps by which this conclusion was reached and leaving a discussion of the previous literature to a later part of this paper. Report of Cases Case1.—A white woman, age 56, was first seen on July 27, 1951. Since the age of 17 recurrent vesicular and bullous lesions have affected the axillae and occasionally the sides of the neck. Attacks tended to occur in the late winter (i. e., July to September in South Africa) and to last for about six weeks. Intervals of freedom varied from a few months to several years. In the past, a few exposures to roentgen rays had always