How a broadly neutralizing antibody grapples with antigenic and conformational diversity in dengue virus.
How a broadly neutralizing antibody grapples with antigenic and conformational diversity in dengue virus.
复制标题
广泛中和抗体如何应对登革热病毒的抗原和构象多样性。
DOI:
10.1016/j.cell.2021.11.020
复制
发表时间:
2021
期刊:
影响因子:
64.5
通讯作者:
Lee,KellyK
中科院分区:
文献类型:
--
作者:
Lee,KellyK
In this issue ofCell,two studies apply powerful structural approaches to probe the modes of interaction between a broadly neutralizing antibody and a conserved epitope found on four dengue virus serotypes and Zika virus. These findings offer new insights into how a broadly neutralizing antibody surmounts antigenic and conformational variation.