High speed multiphoton axial scanning through an optical fiber in a remotely scanned temporal focusing setup.

High speed multiphoton axial scanning through an optical fiber in a remotely scanned temporal focusing setup.
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DOI:
10.1364/boe.2.000080
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发表时间:
2010-12-06
影响因子:
3.4
通讯作者:
Xu C
Xu C
中科院分区:
医学2区
文献类型:
--
作者:
Straub A;Durst ME;Xu C

文献摘要

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同时空间和时间聚焦用于通过单模光纤获取小鼠皮肤的高速(200Hz)、化学特异性轴向扫描。通过调制光纤近端的群延迟色散(GDD),实现了时间焦点的远程扫描。远端不需要移动部件或电子设备。本文提出了一种新型的GDD调制技术,即在折叠光栅对中使用压电双晶片反射镜,以实现大范围的高速GDD调谐。
Simultaneous spatial and temporal focusing is used to acquire high speed (200Hz), chemically specific axial scans of mouse skin through a single-mode fiber. The temporal focus is remotely scanned by modulating the group delay dispersion (GDD) at the proximal end of the fiber. No moving parts or electronics are required at the distal end. A novel GDD modulation technique is implemented using a piezo bimorph mirror in a folded grating pair to achieve a large GDD tuning range at high speed.