Novel HPAIV H5N8 Reassortant (Clade 2.3.4.4b) Detected in Germany
Novel HPAIV H5N8 Reassortant (Clade 2.3.4.4b) Detected in Germany
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DOI：
10.3390/v12030281
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发表时间：
2020-03-01
期刊：
影响因子：
4.7
通讯作者：
Pohlmann, Anne
中科院分区：
文献类型：
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作者：
King, Jacqueline;Schulze, Christoph;Pohlmann, Anne
2020年1月在德国勃兰登堡的一只大白额鹅和2020年2月在德国巴登-符腾堡州一个小农场的家鸡中检测到一种新型H5N8高致病性禽流感病毒(HPAIV)。在Minion平台上进行了全基因组测序，从而能够进行进一步的系统发育分析。2.3.4.4b分支病毒包含欧亚/亚洲/非洲HPAIV H5N8重组体的六个片段和最近在俄罗斯中部野生鸟类中发现的低致病性禽流感H3N8亚型病毒的两个片段。这些新条目继续显示分支2.3.4.4 H5Nx病毒的重新分类潜力，强调了全基因组测序和持续监测的必要性。
A novel H5N8 highly pathogenic avian influenza virus (HPAIV) was detected in a greater white-fronted goose in January 2020 in Brandenburg, Germany, and, in February 2020, in domestic chickens belonging to a smallholding in Baden-Wuerttemberg, Germany. Full-genome sequencing was conducted on the MinION platform, enabling further phylogenetic analyses. The virus of clade 2.3.4.4b holds six segments from a Eurasian/Asian/African HPAIV H5N8 reassortant and two segments from low pathogenic avian influenza H3N8 subtype viruses recently detected in wild birds in Central Russia. These new entries continue to show the reassortment potential of the clade 2.3.4.4 H5Nx viruses, underlining the necessity for full-genome sequencing and continuous surveillance.