IMMUNITY AND DEPRESSION - INSOMNIA, RETARDATION, AND REDUCTION OF NATURAL-KILLER-CELL ACTIVITY
IMMUNITY AND DEPRESSION - INSOMNIA, RETARDATION, AND REDUCTION OF NATURAL-KILLER-CELL ACTIVITY
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DOI：
10.1007/bf01858106
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发表时间：
1994-04-01
影响因子：
3.1
通讯作者：
IRWIN, M
中科院分区：
文献类型：
--
作者：
COVER, H;IRWIN, M
抑郁症患者的自然杀伤 (NK) 细胞活性降低，这可能与特定的抑郁症状有关。本研究表明，在 38 名抑郁症患者中，睡眠障碍和发育迟缓与 NK 活性呈负相关，但与其他抑郁症状无关。研究发现，抑郁症的特定行为变化（例如睡眠障碍和迟缓）可以预测抑郁症细胞毒性水平变异的 16%。
Depressed patients show a reduction of natural killer (NK) cell activity which may be associated with specific depressive symptoms. The present study demonstrated that sleep disturbance and retardation, but not other depressive symptoms, were negatively correlated with NK activity in 38 depressed patients. Specific behavioral changes in depression such as sleep disturbance and retardation were found to predict 16% of the variance of cytotoxicity levels in depression.