Epigenetics: a lasting impression?
Epigenetics: a lasting impression?
复制标题
表观遗传学：持久的印象？
DOI：
10.1111/j.1365-2826.2010.02082.x
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发表时间：
2011
影响因子：
3.2
通讯作者：
Biddie SC
中科院分区：
文献类型：
--
作者：
Biddie SC
Epigenetics is the term that has been classically used to describe inheritable nongenetic factors that regulate genes. Although these factors were originally thought to act in a long time domain only, it is now clear that they can also be highly dynamic, changing over minutes. Transcription factors, including the glucocorticoid, oestrogen and androgen receptors, interact with these epigenetic mechanisms in a very dynamic manner to modify transcription of genes and consequently contribute to physiological processes, health and disease. Modern usage of the term epigenetics encompasses both longer‐term and transient changes and is relevant to multiple biological systems.
