Toward a data infrastructure for the Plant Cell Atlas
Toward a data infrastructure for the Plant Cell Atlas
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DOI：
10.1093/plphys/kiac468
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发表时间：
2022-10-06
期刊：
影响因子：
7.4
通讯作者：
Provart，Nicholas J.
中科院分区：
文献类型：
--
作者：
Fahlgren，Noah;Kapoor，Muskan;Provart，Nicholas J.
我们回顾了如何使用现有的基础设施和平台建立植物细胞图谱的数据基础设施。人类细胞图谱为人类和小鼠单细胞数据开发了广泛的基础设施，而欧洲生物信息学研究所开发了单细胞表达图谱，目前包含几个植物数据集。我们讨论了适当的本体描述植物单细胞实验相关的问题。我们想象这样的基础设施将如何使生物学家和数据科学家在未来几十年内收集植物生物学的新见解，只要这些数据以开放的方式向社区开放。
We review how a data infrastructure for the Plant Cell Atlas might be built using existing infrastructure and platforms. The Human Cell Atlas has developed an extensive infrastructure for human and mouse single cell data, while the European Bioinformatics Institute has developed a Single Cell Expression Atlas, that currently houses several plant data sets. We discuss issues related to appropriate ontologies for describing a plant single cell experiment. We imagine how such an infrastructure will enable biologists and data scientists to glean new insights into plant biology in the coming decades, as long as such data are made accessible to the community in an open manner.