Quantitative analysis of free flap volume changes in head and neck reconstruction

Quantitative analysis of free flap volume changes in head and neck reconstruction
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DOI:
10.1002/hed.21944
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发表时间:
2012-10-01
影响因子:
2.9
通讯作者:
Onoda, Tomoo
Onoda, Tomoo
中科院分区:
医学2区
文献类型:
--
作者:
Yamaguchi, Kazuaki;Kimata, Yoshihiro;Onoda, Tomoo

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本研究的目的是确定游离皮瓣体积在术后长期内是减少还是增加。方法回顾性分析17例患者使用AZE Virtual Place Lexus64三维图像测量游离皮瓣的肌肉和脂肪体积。结果17例患者行腹直肌皮瓣(11例)或股前外侧皮瓣(6例)重建。中位随访时间28.9个月(范围2.148.4个月)。包括40%肌肉在内的皮瓣的总皮瓣体积显著减少(p = 0.011)。平均12个月的最终肌肉体积为50%。无疾病证据患者的最终脂肪体积(平均116.7%)显著高于疾病死亡患者(平均70.3%,p = .007)。结论使用高脂肌比的游离皮瓣是可持续的,并且随着时间的推移可以增加体积,因为移植的脂肪会根据宿主的情况而增加。(c) 2011 Wiley期刊公司头颈,2011年
Background The purpose of this study was to determine whether free flap volume decreases or increases in the long-term postoperative period. Methods We used a retrospective analysis of 17 patients to measure muscle and fat volume in free flap with 3-dimensional (3D) images using the AZE Virtual Place Lexus64. Results Seventeen patients underwent free flap reconstruction with rectus abdominis musculocutaneous flaps (n = 11) or anterolateral thigh flaps (n = 6). Median follow-up was 28.9 months (range, 2.148.4 months). Total flap volume was significantly decreased in flaps including =40% muscle (p = .011). Mean final muscle volume was 50% at an average of 12 months. Final fat volume was significantly higher for cases with no evidence of disease (mean, 116.7%) than for died-of-the-disease cases (mean, 70.3%; p = .007). Conclusion Use of free flaps with a high ratio of fat to muscle is sustainable and can gain volume over time, as transplanted fat can increase depending on host condition. (c) 2011 Wiley Periodicals, Inc. Head Neck, 2011