Echogenic foci with comet-tail artifact in resected thyroid nodules: Not an absolute predictor of benign disease.
Echogenic foci with comet-tail artifact in resected thyroid nodules: Not an absolute predictor of benign disease.
复制标题
在切除的甲状腺结节中具有彗星尾伪影的回声灶：不是良性疾病的绝对预测指标。
DOI：
10.1371/journal.pone.0191505
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Zhao T
中科院分区：
文献类型：
--
作者：
Wu H;Zhang B;Li J;Liu Q;Zhao T
本研究的目的是评估组织学证实的甲状腺结节中具有彗星尾伪影的回声灶的频率，并确定与恶性相关的具有彗星尾伪影的回声灶的类型。我们回顾性分析了2016年1月至2016年9月期间在我院接受甲状腺结节手术的63例患者的甲状腺结节中存在回声灶伴彗星尾伪影的超声检查结果。比较良、恶性结节的声像图表现（回声灶的形态、背景、彗星尾伪影的形态）。在556例患者的962个甲状腺结节中，71个（7.4%）结节超声发现回声灶伴彗星尾伪影，其中25个为良性，46个为恶性。在彗星尾伪影类别的回声灶中，自由分布在囊性成分中的（11/11，100%）均为良性结节，而回声灶的任何部分或彗星尾伪影与实性成分相关的（48/67，71.6%）在恶性结节中更常见（P < 0.001）。良、恶性结节的回声灶和彗星尾形态差异无统计学意义（P = 0.139，P = 0.626）。回声灶伴彗星尾伪影自由分布在囊性成分中可能预示良性结节;与实性成分相关的回声灶不能被认为是良性。
The purpose of this study was to evaluate the frequency of echogenic foci with comet-tail artifact in histologically proven thyroid nodules, and to determine the types of echogenic foci with comet-tail artifact that are associated with malignancy. We retrospectively analyzed the sonographic findings of echogenic foci with comet-tail artifact, present in thyroid nodules in 63 patients who underwent surgery for thyroid nodules at our institution between January 2016 and September 2016. The sonographic findings (appearance and background of echogenic foci, shape of comet-tail artifact) in benign and malignant nodules were compared. Seventy-one (7.4%) nodules with ultrasound finding of echogenic foci with comet-tail artifact were encountered in 962 thyroid nodules of 556 patients; 25 of these were benign, and 46 were malignant. Among the echogenic foci with comet-tail artifact categories, those (11/11, 100%) freely distributed in cystic components were all in benign nodules, whereas those (48/67, 71.6%) any part of echogenic foci or comet-tail artifact associated with solid components, were more common in malignant nodules (P < 0.001). There was no statistically significant difference in the appearance of echogenic foci and the shape of comet-tail between the benign and malignant nodules (P = 0.139, P = 0.626, respectively). Echogenic foci with comet-tail artifact freely distributed in cystic component may predict a benign nodule; those associated with solid components cannot be considered a benign finding.
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