Effect of vibration on skin blood flow in an in vivo microcirculatory model.
Effect of vibration on skin blood flow in an in vivo microcirculatory model.
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DOI：
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发表时间：
2007-12
影响因子：
5.5
通讯作者：
G. Nakagami;H. Sanada;N. Matsui;A. Kitagawa;Hideki Yokogawa;Naomi Sekiya;S. Ichioka;J. Sugama;M. Shibata
中科院分区：
文献类型：
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作者：
G. Nakagami;H. Sanada;N. Matsui;A. Kitagawa;Hideki Yokogawa;Naomi Sekiya;S. Ichioka;J. Sugama;M. Shibata
研究振动对皮肤微循环的影响，探讨临床应用振动防治压疮的可能性。在吸入麻醉下，对雄性无毛小鼠(每组6只)水平施加振动强度为600、800或1000 mVpp，固定频率为47赫兹的振动。对照组(n=6)不接受任何振动。在基础状态和施加振动后的0、5和15分钟，用活体视频显微镜测量静脉血流量。600mVpp组在振动后5min和15min较对照组显著升高(P=0.002和P=0.046)。在振动后5分钟，800mVpp组(P=0.028)和1000mVpp组(P=0.012)的血流量也有所增加，但在15分钟后这些增加有所减弱。这些结果表明，频率为47赫兹的直接皮肤振动可以改善皮肤血流量。本研究进一步支持了振动对短期皮肤血流量增加的作用。
The effect of vibration on skin microcirculation was studied to investigate the possibility of clinical use of vibration to prevent and treat pressure ulcers. Vibrations at a vibrational intensity of 600, 800, or 1,000 mVpp with a fixed frequency of 47 Hz were applied horizontally to the ear of male hairless mice (n = 6 for each group) under inhalation anesthesia. The control group (n = 6) received no vibrations. Venular blood flow was measured by an intravital videomicroscope at the baseline and at 0, 5, and 15 min after the application of vibrations. A significant increase was observed in the 600 mVpp group 5 and 15 min after vibration in comparison to the control group (P = 0.002 and P = 0.046, respectively). We also detected increased blood flow in the 800 mVpp group (P = 0.028) and the 1,000 mVpp group (P = 0.012) 5 min after vibration; however, these increases attenuated after 15 min. These results indicate that direct skin vibration at a frequency of 47 Hz improves skin blood flow. The present study gives further support to the role of vibration on a short-term increase in skin blood flow.