Relationship of prepulse inhibition of the startle reflex to attentional and executive mechanisms in man
Relationship of prepulse inhibition of the startle reflex to attentional and executive mechanisms in man
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DOI：
10.1016/j.ijpsycho.2004.08.002
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发表时间：
2005-02-01
影响因子：
3
通讯作者：
Giakoumaki, SG
中科院分区：
文献类型：
--
作者：
Bitsios, P;Giakoumaki, SG
短导联期惊跳反射的预脉冲抑制（PPI）被认为反映了一种预先注意的“感觉运动门控”机制的运作，这表明预脉冲刺激的加工不应该在其对惊跳的抑制作用之前被调节。为了验证这一假设，我们检查了习惯预脉冲后PPI是否会受到影响。PPI在两个阶段进行测量，其中一个是存在（习惯条件），另一个是不存在（控制条件）脉冲前重复。预脉冲重复有降低预脉冲抑制惊吓反应效果的趋势。我们还探讨了PPI与选择性和持续性注意力和计划能力测试得分的关系。总体PPI表现与计划能力表现指标存在相关性，与选择性注意测验得分呈趋势水平相关，但与持续注意测验得分无相关性。这些初步结果值得进一步调查。(C) 2004 Elsevier B.V.版权所有
Prepulse inhibition (PPI) of the startle reflex at short lead intervals is thought to reflect the operation of a preattentive "sensorimotor gating" mechanism, which suggests that processing of the prepulse stimulus should not be modulated prior to its inhibitory effects on startle. To test this hypothesis, we examined whether PPI is affected following habituation to the prepulse. PPI was measured in two sessions associated with either the presence (habituation condition) or the absence (control condition) of prepulse repetition. There was a trend for prepulse repetition to reduce the effectiveness of that prepulse in inhibiting the startle response. We also explored the relationship of PPI to scores in tests of selective and sustained attention and planning ability. Overall PPI performance was correlated to performance indices of planning ability and there was a trend level correlation with scores in selective but not sustained attention tests. These preliminary results merit further investigation. (C) 2004 Elsevier B.V. All rights reserved.