Coffee consumption is inversely associated with type 2 diabetes in Chinese
Coffee consumption is inversely associated with type 2 diabetes in Chinese
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DOI：
10.1111/j.1365-2362.2010.02455.x
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发表时间：
2011-06-01
影响因子：
5.5
通讯作者：
Lin, Cheng-Chieh
中科院分区：
文献类型：
--
作者：
Lin, Wen-Yuan;Pi-Sunyer, F. Xaiver;Lin, Cheng-Chieh
研究背景咖啡摄入量与2型糖尿病（T2 DM）呈负相关，但在中国人群中的证据有限。我们调查了咖啡消费量和T2 DM之间的关系，在一个人口为基础的队列的中年Chinese.Materials和methodsWe研究了2332名受试者参加了2004年在台湾的台中社区健康研究。咖啡消费量，T2 DM和空腹血糖之间的关系进行了assessed.ResultsThe患病率T2 DM是14个中心点0%和10个中心点4%的男性和女性。校正年龄、体重指数、血压、吸烟、饮酒、嚼槟榔、体力活动、收入、教育水平、脂肪%、蛋白质%、碳水化合物%和镁后，咖啡摄入量与T2 DM呈负相关。习惯喝咖啡的人患2型糖尿病的风险比不喝咖啡的人低38-46%。与不饮酒者相比，根据习惯喝咖啡的受试者，T2 DM的调整后优势比（OR）（< 1，1-6，>= 7次/周）为0中心点77（0中心点52-1中心点13）、0中心点46（0中心点28-0中心点76）和0中心点37（0中心点16-0中心点83）。降低的OR表明咖啡消耗对患有T2 DM的可能性的剂量反应效应（P < 0中心点001）。在新诊断的2型糖尿病患者中也存在类似的关系（P < 0，中心点0.05）。随着咖啡摄入频率的增加，空腹血糖水平逐渐降低（P <0.05）。咖啡可能是中国人T2 DM的保护剂。
P>BackgroundCoffee consumption has been shown to be inversely associated to type 2 diabetes mellitus (T2DM), but evidence in Chinese populations is limited. We investigated the relationship between coffee consumption and T2DM in a population-based cohort of middle-aged Chinese.Materials and methodsWe studied 2332 subjects who participated in the Taichung Community Health Study in Taiwan in 2004. The relationships between coffee consumption, T2DM and fasting glucose were assessed.ResultsThe prevalence of T2DM was 14 center dot 0% and 10 center dot 4% in men and women. After adjustment for age, body mass index, blood pressure, smoking, alcohol drinking, betel nut chewing, physical activity, income, education level, fat%, protein%, carbohydrate% and magnesium, coffee intake was inversely associated with T2DM. Habitual coffee drinkers had 38-46% lower risk of T2DM than nondrinkers. Compared to nondrinkers, the adjusted odds ratios (ORs) for T2DM according to subjects with habitual coffee consumption (< 1, 1-6, >= 7 times per week) were 0 center dot 77 (0 center dot 52-1 center dot 13), 0 center dot 46 (0 center dot 28-0 center dot 76) and 0 center dot 37 (0 center dot 16-0 center dot 83), respectively. The decreasing ORs indicate a dose-response effect of coffee consumption on the likelihood of having T2DM (P < 0 center dot 001). A similar relationship was also evident in newly diagnosed T2DM (P < 0 center dot 05). The adjusted mean fasting glucose levels gradually decreased as the frequency of coffee consumption increased (P < 0 center dot 05).ConclusionsCoffee intake is inversely associated with T2DM in Chinese. Coffee may be a protective agent for T2DM in Chinese.