Autoimmunity of the lacrimal gland.
Autoimmunity of the lacrimal gland.
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泪腺的自身免疫。
DOI：
10.1097/00004397-199403410-00003
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发表时间：
1994
影响因子：
--
通讯作者：
Wood,RL
中科院分区：
文献类型：
--
作者：
Mircheff,AK;Gierow,JP;Wood,RL
泪腺分泌蛋白质、营养素、激素、生长因子和免疫球蛋白的混合物，其在近似等渗的电解质溶液中。泪腺腺泡细胞通过经典的局部分泌机制释放分泌蛋白，例如溶菌酶和乳铁蛋白。腺泡利用转胞吞机制分泌免疫球蛋白，主要是分泌型免疫球蛋白A（伊加）和至少一种蛋白质激素，催乳素[1，2]。泪管细胞含有表皮生长因子（EGF）[3]，它们似乎将其释放到形成的泪腺液和泪腺囊中，在那里它可以作为旁分泌介质发挥作用。
The lacrimal glands secrete a mixture of proteins, nutrients, hormones, growth factors, and immunoglobulins in an approximately isotonic electrolyte solution. Lacrimal'acinar cells release secretory proteins, such as lysozyme and lactoferrin, by the classical merocrine mechanism. The acini use transcytotic mechanisms to secrete immunoglobulins, primarily secretory immunoglobulin A (IgA), and at least one protein hormone, prolactin [1, 2]. Lacrimal duct cells contain epidermal growth factor (EGF)[3], and they appear to release it both into the forming lacrimal gland fluid and into the lacrimal interstitium, where it may function as a paracrine mediator.