Novel Acyl α-Pyronoids, Dictyopyrone A, B, and C, from Dictyostelium Cellular Slime Molds
Novel Acyl α-Pyronoids, Dictyopyrone A, B, and C, from Dictyostelium Cellular Slime Molds
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来自盘基网柄菌细胞粘菌的新型酰基 α-吡喃酮，盘基吡喃酮 A、B 和 C
DOI：
10.1021/jo991338i
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发表时间：
2000
影响因子：
3.6
通讯作者：
Y. Oshima
中科院分区：
文献类型：
--
作者：
Y. Takaya;H. Kikuchi;Y. Terui;J. Komiya;K. Furukawa;K. Seya;S. Motomura;A. Ito;Y. Oshima
为了阐明网柄藻细胞黏菌次级代谢产物的多样性，我们对三种黏菌的组成进行了研究。从其子实体的甲醇提取物中分离得到3个新化合物，即网柄吡喃酮A（1）和B（2）。discoideum和D. rhizopyrone C（3）;长孢霉属它们具有独特的α-吡喃酮部分，其侧链位于C-3位置。通过光谱手段确定了它们的相对结构，并通过1的不对称合成确定了它们的绝对构型。由于这些化合物是从不同种类的网柄黏菌中获得的，因此它们可能是该属共有的一类化合物。
For the elucidation of the diversity of secondary metabolites of Dictyostelium cellular slime molds, we investigate the constituent of three species of slime molds. From the methanol extract of their fruit bodies, we obtained three novel compounds, dictyopyrone A (1) and B (2) from D. discoideum and D. rhizoposium and dictyopyrone C (3) from D. longosporum. They possess a unique α-pyrone moiety with a side chain at the C-3 position. Their relative structures were elucidated by spectral means, and the absolute configuration was confirmed by asymmetric synthesis of 1. Since these compounds were obtained from different species of Dictyostelium slime molds, they may be a type of compound common to this genus.