[A review on the epidemiology of severe fever with thrombocytopenia syndrome].
[A review on the epidemiology of severe fever with thrombocytopenia syndrome].
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DOI：
10.3760/cma.j.cn112338-20210529-00439
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发表时间：
2021-12-10
影响因子：
--
通讯作者：
Liu, W
中科院分区：
文献类型：
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作者：
Li, J C;Wang, Y N;Liu, W
发热伴血小板减少综合征（SFTS）是21世纪世纪发现的一种新的蜱传传染病。这种疾病已在几个亚洲国家报告，包括中国，日本，韩国，越南和缅甸。截至2019年，中国25个省份报告了SFTS病例，其中大部分是山区和丘陵地区的农村居民。大多数SFTS病例呈散发性，但地理分布集中，主要集中在河南、山东、安徽、湖北、辽宁、浙江和江苏省。SFTSV感染主要通过蜱叮咬传播，并可能通过密切接触患者的血液或体液传播。发热、消化道症状、血小板减少、白细胞减少是常见的首发症状，严重者可发生多器官功能衰竭甚至死亡。SFTS报告病例逐渐增多，病死率居高不下，对我国公共卫生构成严重威胁。本文就SFTS的流行病学特征、传播危险因素及临床特点进行综述，以期加深对该病的认识，指导防治工作，降低病死率。
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease discovered in the 21st century. This disease has been reported in several Asian countries, including China, Japan, South Korea, Vietnam, and Myanmar. Until 2019, SFTS cases have been reported in 25 provinces in China, and most of them were rural residents from mountains and hilly regions. Most SFTS cases were sporadic but geographically concentrated, mainly in Henan, Shandong, Anhui, Hubei, Liaoning, Zhejiang, and Jiangsu provinces. SFTSV infection was transmitted predominantly by a tick bite and potentially through close contact with the patient's blood or body fluids. Fever, gastrointestinal symptoms, thrombocytopenia, and leukopenia were common initial manifestations, and multiple organ failure or even death could occur in severe cases. The reported cases of SFTS have been gradually increasing, and the case fatality rate has remained at a high level, posing a severe threat to public health in China. This paper reviewed the epidemiological features, risk factors for disease transmission, and the clinical characteristics of SFTS to gain further knowledge of the disease, guide the prevention and management, and help reduce the case fatality rate.