Gait speed and survival in older adults.
Gait speed and survival in older adults.
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DOI：
10.1001/jama.2010.1923
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发表时间：
2011-01-05
影响因子：
120.7
通讯作者：
Guralnik, Jack
中科院分区：
文献类型：
--
作者：
Studenski, Stephanie;Perera, Subashan;Patel, Kushang;Rosano, Caterina;Faulkner, Kimberly;Inzitari, Marco;Brach, Jennifer;Chandler, Julie;Cawthon, Peggy;Connor, Elizabeth Barrett;Nevitt, Michael;Visser, Marjolein;Kritchevsky, Stephen;Badinelli, Stefania;Harris, Tamara;Newman, Anne B.;Cauley, Jane;Ferrucci, Luigi;Guralnik, Jack
生存估计有助于为老年患者制定个体化的护理目标，但生命表未能考虑到生存中的巨大变异性。体能指标，如步态速度，可能有助于解释可变性，允许临床医生做出更个性化的估计。目的：探讨步速与生存的关系。对9项队列研究(收集于1986至2000年间)进行汇总分析，使用来自社区居住的34 485名65岁或65岁以上老年人的个人数据和基线步速数据，进行6至21年的随访。受试者的平均年龄(SD)为73.5(5.9)岁；女性占59.6%；白人占79.8%；平均步速(SD)为0.92(0.27)m/S。死亡17528例，5年生存率84.8%(可信区间79.6%~88.8%)，10年生存率59.7%(95%可信区间46.5%~70.6%)。在所有研究中，步态速度与生存相关(每0.1m/S的合并风险比，0.88；95%可信区间，0.87-0.90；P<；001)。所有步速范围内的存活率都增加了，每0.1米/S的存活率显著增加。在75岁时，预计在所有步速范围内，男性的10年存活率在19%到87%之间，女性在35%到91%之间。根据年龄、性别和步态速度预测的生存率与基于年龄、性别、活动辅助工具的使用和自我报告的功能或年龄、性别、慢性病、吸烟史、血压、体重指数和住院时间的预测一样准确。在这项对9个选定队列的个体数据的汇集分析中，步态速度与老年人的存活率有关。
Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival. Physical performance measures, such as gait speed, might help account for variability, allowing clinicians to make more individualized estimates. To evaluate the relationship between gait speed and survival. Pooled analysis of 9 cohort studies (collected between 1986 and 2000), using individual data from 34 485 community-dwelling older adults aged 65 years or older with baseline gait speed data, followed up for 6 to 21 years. Participants were a mean (SD) age of 73.5 (5.9) years; 59.6%, women; and 79.8%, white; and had a mean (SD) gait speed of 0.92 (0.27) m/s. Survival rates and life expectancy. There were 17 528 deaths; the overall 5-year survival rate was 84.8% (confidence interval [CI], 79.6%–88.8%)and 10-year survival rate was 59.7% (95%CI, 46.5%–70.6%). Gait speed was associated with survival in all studies (pooled hazard ratio per 0.1 m/s, 0.88; 95% CI, 0.87–0.90; P<. 001). Survival increased across the full range of gait speeds, with significant increments per 0.1 m/s. At age 75, predicted 10-year survival across the range of gait speeds ranged from 19% to 87% in men and from 35% to 91% in women. Predicted survival based on age, sex, and gait speed was as accurate as predicted based on age, sex, use of mobility aids, and self-reported function or as age, sex, chronic conditions, smoking history, blood pressure, body mass index, and hospitalization. In this pooled analysis of individual data from 9 selected cohorts, gait speed was associated with survival in older adults.
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DOI：
10.1093/gerona/62.11.1244
发表时间：
2007-11-01
影响因子：
5.1
作者：
Fitzpatrick, Annette L.;Buchanan, Catherine K.;Williamson, Jeff D.
通讯作者：
Williamson, Jeff D.
影响因子：
120.7
作者：
CUMMINGS, SR;BLACK, DM;VOGT, TM
通讯作者：
VOGT, TM
影响因子：
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作者：
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通讯作者：
Roewer, N
DOI：
10.1111/j.1532-5415.2000.tb03873.x
发表时间：
2000-12-01
影响因子：
6.3
作者：
Ferrucci, L;Bandinelli, S;Guralnik, JM
通讯作者：
Guralnik, JM
影响因子：
3.1
作者：
Jones, Lynnette M.;Waters, Debra L.;Legge, Michael
通讯作者：
Legge, Michael