CROSSED CEREBELLAR DIASCHISIS AND BRAIN RECOVERY AFTER STROKE
CROSSED CEREBELLAR DIASCHISIS AND BRAIN RECOVERY AFTER STROKE
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DOI：
10.1161/01.str.26.1.90
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发表时间：
1995-01-01
期刊：
影响因子：
8.3
通讯作者：
HOPPER, JL
中科院分区：
文献类型：
--
作者：
INFELD, B;DAVIS, SM;HOPPER, JL
背景和目的尽管交叉性小脑功能不能在卒中后被广泛认识，但其临床相关性和系列变化仍存在争议，方法我们对47例急性大脑中皮层梗死患者进行了交叉性小脑功能不能和脑灌注不足的研究，采用Tc-99 m-六甲基丙烯胺肟和单次-在中风发作后72小时内进行光子发射计算机断层扫描。这些患者中有31例在3个月时进行了结局研究; 31例中有15例在乙酰唑胺注射后进行了额外的扫描。28例患者的组织损失通过计算机断层扫描确定，在结局时进行。临床卒中严重程度采用加拿大神经功能量表和Barthel指数进行评估。对22名年龄匹配的健康对照者进行了小脑血流不对称性研究。
Background and Purpose Although crossed cerebellar diaschisis is well recognized after stroke, there is controversy concerning its clinical correlations and serial changes, and little is known about its prognostic value.Methods We studied crossed cerebellar diaschisis and cerebral hypoperfusion in 47 patients with acute middle cerebral cortical infarction using Tc-99m-hexamethylpropyleneamine oxime and single-photon emission computed tomography within 72 hours of stroke onset. Thirty-one of these patients had outcome studies at 3 months; 15 of the 31 underwent an additional scan after acetazolamide injection. Tissue loss was determined with computed tomography, performed at outcome in 28 patients. Clinical stroke severity was assessed with the Canadian Neurological Scale and Barthel Index. Cerebellar blood flow asymmetry was studied in 22 healthy, age-matched control subjects.Results Cerebellar blood flow asymmetry was significant in patients (mean+/-SE, 9.76+/-0.78%; P