Ribosomal protein S14 is encoded by a pair of highly conserved, adjacent genes on the X chromosome of Drosophila melanogaster.
Ribosomal protein S14 is encoded by a pair of highly conserved, adjacent genes on the X chromosome of Drosophila melanogaster.
复制标题
核糖体蛋白 S14 由黑腹果蝇 X 染色体上一对高度保守的相邻基因编码。
DOI：
10.1128/mcb.8.10.4314-4321.1988
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发表时间：
1988
影响因子：
5.3
通讯作者：
Roufa,DJ
中科院分区：
文献类型：
--
作者：
Brown,SJ;Rhoads,DD;Stewart,MJ;VanSlyke,B;Chen,IT;Johnson,TK;Denell,RE;Roufa,DJ
我们描述了aDrosophilaDNA的串联复制基因克隆，其编码的氨基酸序列与人类核糖体蛋白S14和酵母rp59几乎相同。尽管它们的外显子非常相似，但内含子的位置和大小在果蝇、人类和酵母（Saccharomyces cerevisiae）核糖体蛋白基因之间存在根本差异。在胚胎和成体组织中均检测到果蝇rps14基因的转录本，其长度与哺乳动物的S14信息相同。果蝇rps14定位于X染色体7C5-9区。该区间还编码了先前表征的Minute位点M(1)7C。
We describe aDrosophilaDNA clone of tandemly duplicated genes encoding an amino acid sequence nearly identical to human ribosomal protein S14 and yeast rp59. Despite their remarkably similar exons, the locations and sizes of introns differ radically among theDrosophila, human, and yeast (Saccharomyces cerevisiae) ribosomal protein genes. Transcripts of bothDrosophila RPS14genes were detected in embryonic and adult tissues and are the same length as mammalian S14 message.Drosophila RPS14was mapped to region 7C5-9 on the X chromosome. This interval also encodes a previously characterized Minute locus,M(1)7C.