LIMBIC-DEPENDENT RECOGNITION MEMORY IN MONKEYS DEVELOPS EARLY IN INFANCY
LIMBIC-DEPENDENT RECOGNITION MEMORY IN MONKEYS DEVELOPS EARLY IN INFANCY
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DOI：
10.1097/00001756-199301000-00020
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发表时间：
1993-01-01
期刊：
影响因子：
1.7
通讯作者：
HAGGER, C
中科院分区：
文献类型：
--
作者：
BACHEVALIER, J;BRICKSON, M;HAGGER, C
婴儿健忘症，即缺乏婴儿期和幼儿期的记忆，被归因于婴儿期边缘系统的不成熟。与这种观点相反，我们现在报告说，边缘依赖性识别记忆早在一个月大的猴子中就存在。通过配对比较优先寻找任务测量的记忆，通常存在于出生后第一个月的婴儿猴中，在杏仁复合体和海马结构受损后不存在，这表明边缘系统结构即使在这个早期也对视觉识别记忆做出了关键贡献。这一发现重新开启了导致婴儿健忘症的神经不成熟的问题。
INFANTILE amnesia, the absence of memories from infancy and early childhood, has been attributed to an immaturity of the limbic system in infancy. Contrary to this view, we now report that limbic-dependent recognition memory is present as early as one month of age in monkeys. Memory measured by the paired-comparison preferential looking task, normally present in infant monkeys within the first month of life, is absent after damage to the amygdaloid complex and hippocampal formation, suggesting that limbic structures make a critical contribution to visual recognition memory even at this early age. The findings reopen the question of the locus of the neural immaturity that underlies infantile amnesia.