Neurophysiological distinction of action words in the fronto-central cortex
Neurophysiological distinction of action words in the fronto-central cortex
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DOI：
10.1002/hbm.10157
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发表时间：
2004-03-01
影响因子：
4.8
通讯作者：
Pulvermüller, F
中科院分区：
文献类型：
--
作者：
Hauk, O;Pulvermüller, F
有人认为，涉及腿部、手臂和面部运动（例如踢、挑、舔）的动作词的处理会导致不同的神经生理活动模式。我们使用多通道脑电图和头部内分布式电流源的波束形成器估计来解决这个问题。与腿、手臂和面部相关的单词的类别与重要的心理语言学因素进行了仔细匹配，包括词频、可形象性、效价和唤醒度，并在行为研究中评估它们的语义关联。通过 64 个头皮电极记录脑电图，同时在阅读任务中以视觉方式呈现刺激。我们应用线性波束形成器技术来获得单词诱发电位背后的源的最佳估计。这些表明皮质额叶区域的激活存在差异，包括初级运动、前运动和前额叶部位。与面部或手臂相关的单词相比，腿部单词对背侧额顶叶区域的激活更强烈，而面部单词在左侧下额叶区域产生的活动更多。在右半球，手臂语言激活了额侧区域。我们在语言神经生物学模型的框架中解释了这些发现，并讨论了前运动皮层镜像神经元在语言处理中的可能作用。 (C) 2004 Wiley-Liss, Inc.
It has been suggested that the processing of action words referring to leg, arm, and face movements (e.g., to kick, to pick, to lick) leads to distinct patterns of neurophysiological activity. We addressed this issue using multi-channel EEG and beam-former estimates of distributed current sources within the head. The categories of leg-, arm-, and face-related words were carefully matched for important psycholinguistic factors, including word frequency, imageability, valence, and arousal, and evaluated in a behavioral study for their semantic associations. EEG was recorded from 64 scalp electrodes while stimuli were presented visually in a reading task. We applied a linear beam-former technique to obtain optimal estimates of the sources underlying the word-evoked potentials. These suggested differential activation in frontal areas of the cortex, including primary motor, pre-motor, and pre-frontal sites. Leg words activated dorsal fronto-parietal areas more strongly than face- or arm-related words, whereas face-words produced more activity at left inferior-frontal sites. In the right hemisphere, arm-words activated lateral-frontal areas. We interpret the findings in the framework of a neurobiological model of language and discuss the possible role of mirror neurons in the premotor cortex in language processing. (C) 2004 Wiley-Liss, Inc.