Diverse bacteria are pathogens of Caenorhabditis elegans

Diverse bacteria are pathogens of Caenorhabditis elegans
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DOI:
10.1128/iai.70.8.4705-4707.2002
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发表时间:
2002-08-01
影响因子:
3.1
通讯作者:
Ewbank, JJ
Ewbank, JJ
中科院分区:
医学2区
文献类型:
--
作者:
Couillault, C;Ewbank, JJ

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无脊椎动物作为模式系统,在实践上和伦理上都很有吸引力,越来越被认为与细菌发病机制的研究有关。我们在这里展示了线虫对令人惊讶的广泛的细菌的敏感性,并可能构成一个有用的模型来研究病原体和共生体。
Practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. We show here that the nematode Caenorhabditis elegans is susceptible to a surprisingly broad range of bacteria and may constitute a useful model for the study of both pathogens and symbionts.