ELEVATED PLASMA HOMOCYSTEINE IN ALCOHOLICS
ELEVATED PLASMA HOMOCYSTEINE IN ALCOHOLICS
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DOI：
10.1111/j.1530-0277.1993.tb00820.x
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发表时间：
1993-06-01
影响因子：
3.2
通讯作者：
FRANK, A
中科院分区：
文献类型：
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作者：
HULTBERG, B;BERGLUND, M;FRANK, A
一个显着较高的血浆同型半胱氨酸浓度与对照组相比，注意到在一组酗酒者（n = 42）住院戒毒。在入院后1或2周内血浆同型半胱氨酸浓度达到正常。在另一组戒酒者（n = 16）血浆同型半胱氨酸没有偏离对照组。由于高同型半胱氨酸血症与早发性血管疾病有关，我们推测酗酒者血浆同型半胱氨酸水平升高可能导致这些患者中风发病率增加。
A significantly higher concentration of plasma homocysteine compared with controls was noted in a group of alcoholics (n = 42) hospitalized for detoxication. Normal concentrations of plasma homocysteine were reached within 1 or 2 weeks after admission to the hospital. In another group of abstinent alcoholics (n = 16) plasma homocysteine did not deviate from that of controls. Since hyperhomocysteinemia has been associated with premature vascular disease, we speculate that the increased plasma homocysteine in alcoholics might cause the increased incidence of stroke found in these patients.