All-electrodeposited amorphous MoS @ZnO core-shell nanorod arrays for self-powered visible-light-activated photoelectrochemical tobramycin aptasensing
All-electrodeposited amorphous MoS @ZnO core-shell nanorod arrays for self-powered visible-light-activated photoelectrochemical tobramycin aptasensing
复制标题
全电沉积非晶MoS@ZnO核壳纳米棒阵列用于自供电可见光激活光电化学妥布霉素适体传感
DOI：
10.1016/j.bios.2019.04.019
复制
发表时间：
2019
影响因子：
12.6
通讯作者：
Wenbo Song
中科院分区：
文献类型：
--
作者：
Mengxiang Shang;Jinling Zhang;Hui Qi;Yao Gao;Jianyue Yan;Wenbo Song
具有高效可见光吸收和快速电荷传输速率的高性能光电极的设计和构建对于开发光电化学（PEC）传感器至关重要。在此，通过简单的全电化学策略，在氧化铟锡（ITO）上均匀生长了排列良好的非晶MoSx（a-MoSx）@ZnO核壳纳米棒阵列。同时提高了 PEC 性能和可见光区域的稳定性。这些可能归因于定向 ZnO 纳米棒内快速电子转移路径的协同效应和结合 a-MoSx 时扩展的可见光吸收，以及两种 PEC 材料之间有利的能带排列。以妥布霉素结合适配体为识别元件，首次成功制备了妥布霉素自供电PEC适配体传感器。该传感器在0.010-50ng/mL的宽线性范围内表现出快速响应，并具有良好的稳定性和重现性。检测限低至5.7pg/mL。在 0V（vs.SCE）下实现了血清样品中妥布霉素的超灵敏和高亲和力测定，具有所需的准确性和令人满意的回收率。这项工作揭示了基于全电沉积 a-MoSx@ZnO NR 阵列的光阳极在自供电 PEC 生物测定中在妥布霉素相关疾病诊断中的应用前景。
The design and construction of high-performance photoelectrode with efficient visible-light absorption and fast charge transport rate are crucial to developing photoelectrochemical (PEC) sensor. Herein, a well-aligned amorphous MoSx(a-MoSx)@ZnO core-shell nanorod arrays was uniformly grown on indium tin oxide (ITO) via a facile all-electrochemical strategy. Simultaneous boosted PEC performance and stability in the visible region were obtained. Those could be attributed to the collaboration effect of fast electron transfer path within the oriented ZnO nanorod and extended visible-light absorption upon combining a-MoSx, as well as favorable energy-band alignment between the two PEC materials. By employing tobramycin-binding aptamer as recognition element, a self-powered PEC aptasensor for tobramycin was successfully fabricated for the first time. The sensor exhibited a rapid response in a wide linear range of 0.010–50 ng/mL with good stability and reproducibility. The detection limit was as low as 5.7 pg/mL. Ultrasensitive and high-affinitive determination of tobramycin in serum samples was realized at 0 V (vs.SCE) with desired accuracy and satisfactory recovery. This work reveals the promising application of all-electrodeposited a-MoSx@ZnO NR arrays-based photoanode for self-powered PEC bioassay in the tobramycin-related disease diagnosis.