Free-breathing Sparse Sampling Cine MR Imaging with Iterative Reconstruction for the Assessment of Left Ventricular Function and Mass at 3.0 T-猫眼课题宝

DOI：

10.1148/radiol.2016151002

发表时间：

2017-01-01

期刊：

RADIOLOGY

影响因子：

19.7

通讯作者：

中科院分区：

医学1区

文献类型：

作者：

Sudarski, Sonja;Henzler, Thomas;Papavassiliu, Theano

目的：前瞻性评价以稀疏数据采样和迭代重建(SSIR)为特征的二维实时电影真快速成像稳态进动磁共振(MR)序列在3.0T的屏气(BH)指令和不屏气(BH)指令下进行左心室(LV)分析的准确性。材料和方法：10名对照组(平均年龄35岁；范围25-56岁)和60名计划接受常规心脏检查的患者(平均年龄58岁；年龄20-86岁)进行了全采样分段多BH电影序列(参考标准)和原型欠采样SSIR序列在单次BH和自由呼吸期间(非BH成像)。对左心功能和左心室重量进行定量分析。结果：与对照组结果相似，60例患者与单纯性高血压SSIR(r=0.93~0.99)和非高血压SSIR(r=0.92~0.98)的左心室射血分数(EF)、容量和质量(P&lt；0001)具有良好的相关性。无论屏气与否，SSIR(参考标准：163.9 g+/-6 58.9，单BH SSIR：178.5 g+/-6 62.0[P&lt；0001]，非BH SSIR：175.3 g 6 63.7[P，0001])高估了LV舒张末质量，其他参数差异无统计学意义(EF：49.3%611.9，单BH SSIR为48.8%6 11.8，非BH SSIR为48.8%6 11)；P=.03和P=.12)。Bland-Altman分析显示，与EF、体积和质量的参考测量标准相比，单一BH SSIR和非BH SSIR的测量误差相似。结论：在3.0T时使用SSIR评估左心功能不低于参考标准，而与BH命令无关。然而，SSIR高估了LV质量。(C)RSNA 2017

Purpose: To prospectively evaluate the accuracy of left ventricle (LV) analysis with a two-dimensional real-time cine true fast imaging with steady-state precession (trueFISP) magnetic resonance (MR) imaging sequence featuring sparse data sampling with iterative reconstruction (SSIR) performed with and without breath-hold (BH) commands at 3.0 T.Materials and Methods: Ten control subjects (mean age, 35 years; range, 25-56 years) and 60 patients scheduled to undergo a routine cardiac examination that included LV analysis (mean age, 58 years; range, 20-86 years) underwent a fully sampled segmented multiple BH cine sequence (standard of reference) and a prototype undersampled SSIR sequence performed during a single BH and during free breathing (non-BH imaging). Quantitative analysis of LV function and mass was performed. Linear regression, Bland-Altman analysis, and paired t testing were performed.Results: Similar to the results in control subjects, analysis of the 60 patients showed excellent correlation with the standard of reference for single-BH SSIR (r = 0.93-0.99) and non-BH SSIR (r = 0.92-0.98) for LV ejection fraction (EF), volume, and mass (P < 0001 for all). Irrespective of breath holding, LV end-diastolic mass was overestimated with SSIR (standard of reference: 163.9 g +/- 6 58.9, single-BH SSIR: 178.5 g +/- 6 62.0 [P < 0001], non-BH SSIR: 175.3 g 6 63.7 [ P,.0001]); the other parameters were not significantly different (EF: 49.3% 6 11.9 with standard of reference, 48.8% 6 11.8 with single-BH SSIR, 48.8% 6 11 with non- BH SSIR; P =.03 and P =.12, respectively). Bland-Altman analysis showed similar measurement errors for single-BH SSIR and non-BH SSIR when compared with standard of reference measurements for EF, volume, and mass.Conclusion: Assessment of LV function with SSIR at 3.0 T is noninferior to the standard of reference irrespective of BH commands. LV mass, however, is overestimated with SSIR. (C) RSNA 2017

Free-breathing Sparse Sampling Cine MR Imaging with Iterative Reconstruction for the Assessment of Left Ventricular Function and Mass at 3.0 T

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