Effects of long-term intake of a fine-grained diet on the mouse masseter muscle.
Effects of long-term intake of a fine-grained diet on the mouse masseter muscle.
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长期摄入细粮饮食对小鼠咬肌的影响。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
M. Kumegawa
中科院分区：
文献类型：
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作者：
N. Maeda;T. Kawasaki;K. Osawa;Y. Yamamoto;H. Sumida;T. Masuda;M. Kumegawa
本文用组织化学和形态计量学方法研究了不同时期喂饲细粒饲料的小鼠咬肌肌纤维。与对照组小鼠相比，喂食细粒饲料的小鼠梭外肌纤维和梭内肌纤维的直径均随时间推移而降低。在出生后第20天断奶后维持特殊饮食160天的动物中，饮食对肌梭直径的影响是严重的，并且每种类型的红色和白色纤维的直径显著小于对照动物。但在对照组和治疗组小鼠之间的中间纤维直径没有显著差异。出乎意料的是，在出生后第180天后，在饮食喂养的小鼠中观察到直径小于红色纤维的白色纤维，尽管在对照动物中检测不到具有如此小直径的白色纤维。梭外和梭内肌纤维琥珀酸脱氢酶活性均降低。此外，在断奶后130和160天喂食饲料的小鼠中，没有环状螺旋末端的肌梭数量增加，尽管对照动物中这些肌梭也增加。长时间饲喂该饲料的动物，外囊和初级末梢的直径也显著减小。随着时间的推移，细粒饲料对小鼠咬肌的这些影响变得更加明显。
Muscle fibers of the masseter muscle of mice which had been fed a fine-grained diet for various periods were studied histochemically and morphometrically. The diameters of both extrafusal and intrafusal muscle fibers decreased with time in mice fed a fine-grained diet, compared with those of control mice. In animals maintained on the special diet for 160 days after weaning at the 20th postnatal day, the effects of the diet on the diameter of muscle spindles were severe, and the diameter of each type of red and white fibers was significantly smaller than those of control animals. But a significant difference was not recognized in the diameter of intermediate fibers between control and treated mice. Unexpectedly, white fibers having a smaller diameter than red fibers were observed in diet-fed mice after the 180th postnatal day, although white fibers having such small diameter were not detectable in control animals. Succinic dehydrogenase activities were decreased in both extrafusal and intrafusal fibers of experimental animals. Moreover, muscle spindles with no annulospiral endings were increased in number in mice fed the diet for 130 and 160 days after weaning, although those spindles also increased in control animals. The diameters of outer capsules and primary endings were also significantly decreased in the animals kept on the diet for a long time. These effects of the fine-grained diet on the mouse masseter muscle became severer with time.