A Variant Guillain-Barré Syndrome with Anti-Ganglioside Complex Antibody
A Variant Guillain-Barré Syndrome with Anti-Ganglioside Complex Antibody
复制标题
具有抗神经节苷脂复合物抗体的变异型吉兰-巴利综合征
DOI：
10.18700/jnc.180073
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发表时间：
2018
影响因子：
--
通讯作者：
Nam Jun Kim
中科院分区：
文献类型：
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作者：
S. Huh;So;Jin;Won Gu Lee;Jong Kuk Kim;Yoon Bw;Nam Jun Kim
背景：最近，在吉兰-巴利综合征的各种亚型中发现了抗神经节苷脂复合物（GSC）抗体。 GSC 是由两个单独的神经节苷脂分子形成的新型糖表位。病例报告：我们介绍了一名患有重叠米勒·费希尔综合征和急性延髓麻痹的 36 岁男性，他的抗 GSC 抗体提供了诊断的稳健性。结论：对于表现出非典型表现且对每种神经节苷脂抗体反应呈阴性的患者，抗 GSC 检测可能被认为很重要。神经临界护理杂志 2018；11(2):134-136
Background: Recently, anti-ganglioside complex (GSC) antibodies were discovered among the various subtypes of Guillain-Barré syndrome. GSC is the novel glycoepitopes formed by two individual ganglioside molecules. Case Report: We present a 36-year-old man with overlap Miller Fisher syndrome and acute bulbar palsy who had anti-GSC antibody that provided diagnostic robustness. Conclusion: Anti-GSC testing could be considered important in patients who show atypical manifestation with negative antibody reaction against each constituent ganglioside. J Neurocrit Care 2018;11(2):134-136