Loss of TET2 Tips the Scales Toward Tumorigenesis.
Loss of TET2 Tips the Scales Toward Tumorigenesis.
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DOI:
10.1016/j.jid.2021.11.023
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发表时间:
2022-05
影响因子:
6.5
通讯作者:
Capell, Brian C.
中科院分区:
文献类型:
--
作者:
Capell, Brian C.
DNA methylation and demethylation function in the balance between cellular differentiation and cancer. Although the roles of DNA methyltransferases have been extensively explored in epidermal biology, ten-eleven translocation (TET) demethylase enzymes are poorly understood. In their new article in the Journal of Investigative Dermatology, Boudra et al. present evidence for a tumor-suppressive role of TET2 and its regulation of 5-hydroxymethylcytosine in the prevention of squamous cell carcinomas.
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影响因子:
64.8
作者:
通讯作者:
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影响因子:
8.8
作者:
Ito, Kyoko;Lee, Joun;Ito, Keisuke
通讯作者:
Ito, Keisuke
影响因子:
6.5
作者:
Boudra, Rafik;Woappi, Yvon;Wang, Diana;Xu, Shuyun;Wells, Michael;Schmults, Chrysalyne D.;Lian, Christine G.;Ramsey, Matthew R.
通讯作者:
Ramsey, Matthew R.
影响因子:
7.7
作者:
Rinaldi L;Avgustinova A;Martín M;Datta D;Solanas G;Prats N;Benitah SA
通讯作者:
Benitah SA
DOI:
10.1016/j.jid.2019.10.016
发表时间:
2020-06
期刊:
The Journal of investigative dermatology
影响因子:
--
作者:
Li F;Yuan CW;Xu S;Zu T;Woappi Y;Lee CAA;Abarzua P;Wells M;Ramsey MR;Frank NY;Wu X;Mandinova A;Frank MH;Lian CG;Murphy GF
通讯作者:
Murphy GF