Prenatal Substance Use and Perceptions of Parent and Partner Use Using the 4P's Plus Screener.
Prenatal Substance Use and Perceptions of Parent and Partner Use Using the 4P's Plus Screener.
复制标题
使用 4Ps Plus 筛查仪了解产前药物使用情况以及父母和伴侣使用药物的看法。
DOI：
10.1007/s10995-018-2647-2
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发表时间：
2019
影响因子：
2.3
通讯作者：
Coleman-Cowger,VictoriaH
中科院分区：
文献类型：
--
作者：
Oga,EmmanuelA;Peters,EricaN;Mark,Katrina;Trocin,Kathleen;Coleman-Cowger,VictoriaH
背景建议产前进行药物使用筛查。4 P's Plus screener包括父母和伴侣使用有问题物质的问题，这些问题在危险分层中没有考虑。ObjectivesThis research examined the：（1）自我报告的父母和伴侣使用有问题物质的患病率，以及与经生化验证的产前物质使用的关联;（2）自我报告的父母/伴侣使用物质的感知作为产前物质使用的代理的效用;和（3）在何种程度上的敏感性的4P的加可以增加考虑父母/合作伙伴的问题，在risk stratification.MethodsA方便的样本500名孕妇之间招募2017年1月和2018年1月。参与者完成了4P's Plus，并提供尿液进行药物检测。有问题的父母/合作伙伴的物质使用问题的诊断效用进行了评估，然后相比，4P的加使用的设计，并与这2个问题包括在riskstratified.ResultsHalf（51%）的受访者报告，无论是合作伙伴或父母有问题的物质使用的4P的加。当伴侣或父母使用有问题的物质被认为是产前物质使用的代理，敏感性为65%，特异性为55%。按预期使用时，灵敏度为94%，特异性为29%。包括伴侣/父母问题的敏感性增加到96%，但特异性降低（19%）。伴侣药物使用和伴侣/父母联合使用与产前药物使用相关[校正比值比（aOR）：2.0（1.2，2.4; p = 0.006）; aOR = 1.6（1.1，2.5，p = 0.04）]. 4P's Plus的实践敏感性结论可能会随着在风险分层中纳入自我报告的有问题的伴侣/母体物质使用项目而改善。
BackgroundPrenatal substance use screening is recommended. The 4 P’s Plus screener includes questions on perceived problematic substance use in parents and partner that are not considered in risk stratification.ObjectivesThis research examined the: (1) prevalence of self-reported problematic parental and partner substance use and associations with biochemically-verified prenatal substance use; (2) utility of self-reported perceptions of parent/partner substance use as proxies for prenatal substance use; and (3) degree to which the sensitivity of the 4P’s Plus can be augmented with consideration of parent/partner questions in risk stratification.MethodsA convenience sample of 500 pregnant women was recruited between January 2017 and January 2018. Participants completed the 4P’s Plus and provided urine for drug testing. Diagnostic utility of problematic parent/partner substance use questions was assessed, then compared to the 4P’s Plus used as designed, and to the 4P’s Plus used with these 2 questions included in risk stratification.ResultsHalf (51%) of respondents reported either partner or parental problematic substance use. When partner or parent problematic substance use were considered as proxies for prenatal substance use, sensitivity was 65% and specificity was 55%. When used as intended, sensitivity was 94% and specificity was 29%. Including partner/parent questions increased sensitivity to 96% but lowered specificity (19%). Partner substance use and combined partner/parent use were associated with prenatal substance use [adjusted odds ratio (aOR): 2.0 (1.2, 2.4; p = 0.006); aOR = 1.6 (1.1, 2.5, p = 0.04)].Conclusions for PracticeSensitivity of the 4P’s Plus may improve with inclusion of self-reported problematic partner/parent substance use items in risk stratification.