MascotDatfile: An open-source library to fully parse and analyse MASCOT MS/MS search results

MascotDatfile: An open-source library to fully parse and analyse MASCOT MS/MS search results
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DOI:
10.1002/pmic.200600682
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发表时间:
2007-02-01
期刊:
影响因子:
3.4
通讯作者:
Gevaert, Kris
Gevaert, Kris
中科院分区:
生物学3区
文献类型:
--
作者:
Helsens, Kenny;Martens, Lennart;Gevaert, Kris

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MS-based protein identification is an important part of both gel-based and gel-free proteome studies. The MASCOT search engine (http://www.matrixscience.com) provides one of the most popular automated algorithms for this task. Here we present an open-source software library written in Java that parses raw MASCOT results into an easily accessible and fully functional object model (http://genesis.ugent.be/MascotDatfile). Several scripts based on this library are provided as examples, allowing direct automation of important routine tasks involved in processing peptide identifications.