Smoke constituent exposure and smoking topography of adolescent daily cigarette smokers
Smoke constituent exposure and smoking topography of adolescent daily cigarette smokers
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DOI：
10.1080/1462220042000282537
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发表时间：
2004-10-01
影响因子：
4.7
通讯作者：
Ahijevych, K
中科院分区：
文献类型：
--
作者：
Wood, T;Wewers, ME;Ahijevych, K
青少年吸烟率是一个主要的健康问题，24.4%的青少年报告在过去30天内吸烟，15.8%的青少年认为每天吸烟。本研究的目的是描述青少年日常吸烟者的生物行为尼古丁依赖，烟雾成分暴露和吸烟地形。尼古丁依赖的生物标志物（尼古丁增加，一氧化碳[CO]增加和可替宁水平）与现有的自我报告措施（改良的Fagerstrom耐受性问卷[mFTQ]和吸烟动机量表）之间的关系进行了检查。性别差异的特点。研究招募了50名13-18岁的青少年，其中50%为女性。CO，血浆尼古丁水平吸烟前和吸烟后，可替宁和吸烟地形测量期间与参与者的日常香烟吸烟回合。吸烟前至吸烟后的平均CO增加为7.2 +/- 3.6 ppm，基线可替宁水平平均为224.0 +/- 169.6 ng/ml，尼古丁增加平均为23.4 +/- 21.7 ng/ml。每支烟的平均抽吸量为14.2 +/- 6.3。男性有显着较高的总吞吐量，但相似的烟雾成分暴露于女性，和更高的处理香烟吸烟的动机。在回归分析中，基线可替宁浓度所示的烟草使用差异的35%可以通过mFTQ测量的最大抽吸持续时间、吸烟后CO水平和尼古丁依赖性来解释。结果表明，青少年有相当大的烟雾成分暴露和尼古丁依赖，这表明适当的戒烟治疗的重要性。
Adolescent smoking prevalence is a major health concern, with 24.4% reporting smoking in the past 30 days and 15.8% considered daily smokers. The purpose of this study was to characterize biobehavioral nicotine dependence, smoke constituent exposure and smoking topography in adolescent daily smokers. Relationships among biological markers of nicotine dependence (nicotine boost, carbon monoxide [CO] boost and cotinine levels) with existing self-report measures (modified Fagerstrom Tolerance Questionnaire [mFTQ] and the motivations for smoking scale) were examined. Gender differences were characterized. Fifty adolescents 13-18 years old were recruited for the study, 50% female. CO, plasma nicotine levels pre- and postcigarette, cotinine, and smoking topography were measured during a smoking bout with participant's usual cigarette. Average CO boost, pre- to postcigarette was 7.2 +/- 3.6 ppm, baseline cotinine level averaged 224.0 +/- 169.6 ng/ml and nicotine boost averaged 23.4 +/- 21.7 ng/ml. Mean puffs per cigarette was 14.2 +/- 6.3. Males had significantly higher total puff volumes, but similar smoke constituent exposure to females, and higher handling of cigarettes as smoking motive. In regression analysis, 35% of variance in tobacco use, as indicated by baseline cotinine concentration, was explained by maximum puff duration, postcigarette CO level, and nicotine dependence, as measured by the mFTQ. Results indicated adolescents had considerable smoke constituent exposure and nicotine dependence suggesting the importance of appropriate smoking cessation treatment.