Extraskeletal myxoid chondrosarcoma--a clinicopathologic and electron microscopic study.
Extraskeletal myxoid chondrosarcoma--a clinicopathologic and electron microscopic study.
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骨外粘液样软骨肉瘤——临床病理学和电子显微镜研究。
DOI：
10.1093/jmicro/dfl009
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
N. Shinohara
中科院分区：
文献类型：
--
作者：
M. Tsuneyoshi;M. Enjoji;H. Iwasaki;N. Shinohara
本文报告603例软组织肉瘤中14例皮肤外粘液样软骨肉瘤的临床病理资料。初次活检时患者的年龄范围为16至69岁。肿瘤主要发生在下肢，包括臀部（10例），组织学上包括索和股的小嗜酸性细胞，偶尔空泡细胞在丰富的粘液基质硫酸软骨素组成。4例电镜观察显示肿瘤细胞由成软骨细胞向未分化间充质细胞分化。形态学研究表明，皮肤外粘液样软骨肉瘤包括所谓的脊索样肉瘤，作为一种变体。
This clinicopathologic study concerns 14 cases of extraskeletal myxoid chondrosarcoma from among 603 cases of soft tissue sarcomas. The ages of the patients at the time of initial biopsy ranged from 16 to 69 years. The tumors mainly arose in the lower extremities including buttocks (10 cases), and consisted histologically in cords and strands of small acidophilic cells with occasional vacuolated cells in an abundant myxoid matrix composed of chondroitin sulfate. Electron microscopy in four revealed a continuum of cell differentiation of the tumor cells from chondroblastic cell to undifferentiated mesenchymal cell. Morphological studies indicated that the extraskeletal myxoid chondrosarcoma included so-called chordoid sarcoma, as a variant.