Rapid fabrication of pressure-driven open-channel microfluidic devices in omniphobic RF paper

Rapid fabrication of pressure-driven open-channel microfluidic devices in omniphobic RF paper
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DOI:
10.1039/c3lc50371b
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发表时间:
2013-01-01
期刊:
影响因子:
6.1
通讯作者:
Whitesides, George M.
Whitesides, George M.
中科院分区:
工程技术1区
文献类型:
--
作者:
Glavan, Ana C.;Martinez, Ramses V.;Whitesides, George M.

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本文描述了使用工艺切割工具在无所不在的纸中雕刻出横向尺寸为45-300微米的压力驱动、开放通道微流控系统。使用氟化烷基三氯硅烷的气相硅烷化使纸张无所不在,但保留了其高透气性和机械性能。当用胶带密封时,雕刻的通道形成了能够在低雷诺数区域(即层流)引导液体传输的管道。这些设备与复杂的流体兼容,如油中的水滴。无所不用纸和工艺切割器的结合使新型阀门和开关的开发成为可能,例如“折叠阀”和“多孔开关”,它们提供了控制流体流动的新方法。
This paper describes the fabrication of pressure-driven, open-channel microfluidic systems with lateral dimensions of 45-300 microns carved in omniphobic paper using a craft-cutting tool. Vapor phase silanization with a fluorinated alkyltrichlorosilane renders paper omniphobic, but preserves its high gas permeability and mechanical properties. When sealed with tape, the carved channels form conduits capable of guiding liquid transport in the low-Reynolds number regime (i.e. laminar flow). These devices are compatible with complex fluids such as droplets of water in oil. The combination of omniphobic paper and a craft cutter enables the development of new types of valves and switches, such as "fold valves'' and "porous switches,'' which provide new methods to control fluid flow.