Relationship between indices of Humphrey perimetry and Frequency Doubling Technology perimetry in glaucoma
Relationship between indices of Humphrey perimetry and Frequency Doubling Technology perimetry in glaucoma
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DOI：
10.1097/00061198-200404000-00006
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发表时间：
2004-04-01
影响因子：
2
通讯作者：
Abe, H
中科院分区：
文献类型：
--
作者：
Fukushima, A;Shirakashi, M;Abe, H
目的：研究Humphrey视野检查与倍频技术（FDT）视野检查指标之间的相关性在青光眼早期和晚期是否存在差异。方法：本研究纳入200名原发性开角型青光眼或正常眼压性青光眼患者的200只眼。根据使用 Humphrey Full-Threshold 30-2 程序对所有眼睛进行的一组测量获得的平均偏差 (MD) 的中值 (-4.51 dB)（分类 1；分别为 n = 100 和 100）或最大值和最小值的平均值 (-11.90 dB)（分类 2；分别为 n = 165 和 35）将眼睛分为早期和晚期。使用线性回归分析评估 MD (H-MD) 或模式标准差 (PSD) (H-PSD) 与 MD (F-MD) 或 PSD (F-PSD)（通过 FDT 视野计的全阈值 N-30 程序计算）之间的相关性。分别为 0.713；P < 0.001）和 F-PSD（r = 0.731；P < 0.001）。在分类 I 和分类 2 中，H-MD 和 H-PSD 在早期和后期分别与 F-MD 和 F-PSD 显着相关。然而，在各分类中，H-MD和F-MD之间的相关性在两个阶段之间存在显着差异（分类1；P < 0.001；分类2，P = 0.003），而H-PSD和F-PSD之间的相关性在两个阶段之间没有显着差异。结论：青光眼早期和晚期之间H-MD和F-MD之间的相关程度存在差异。
Purpose: To study whether the correlation between indices of Humphrey perimetry and Frequency Doubling Technology (FDT) perimetry differs in the early and later stages of glaucoma.Methods: This study included 200 eyes of 200 patients with primary open-angle glaucoma or normal-tension glaucoma. The eyes were classified into the early and later stages by the median value (-4.51 dB) (Classification 1; n = 100 and 100, respectively) or the average value of the maximum and minimum values (-11.90 dB) (Classification 2; n = 165 and 35, respectively) of mean deviation (MD) obtained from a set of measurements with the Humphrey Full-Threshold 30-2 program in all eyes. The correlation between MD (H-MD) or pattern standard deviation (PSD) (H-PSD), as obtained from another set of measurements with the Humphrey Full-Threshold 30-2 program, and MD (F-MD) or PSD (F-PSD), as calculated by the Full-Threshold N-30 program of FDT perimetry, were evaluated using linear regression analysis.Results: Overall, H-MD and H-PSD significantly correlated with F-MD (r = 0.713; P < 0.001) and F-PSD (r = 0.731; P < 0.001), respectively. In each of Classifications I and 2, H-MD and H-PSD significantly correlated with F-MD and F-PSD, respectively, both in the early and later stages. However, in each classification, the correlation between H-MD and F-MD differed significantly between the two stages (Classification 1; P < 0.001; Classification 2, P = 0.003), while the correlation between H-PSD and F-PSD did not differ significantly between the two stages.Conclusion: The degree of correlation between H-MD and F-MD differed between the early and later stages of glaucoma.