Respiratory pattern changes during costovertebral joint movement.
Respiratory pattern changes during costovertebral joint movement.
复制标题
肋椎关节运动期间呼吸模式发生变化。
DOI：
10.1152/jappl.1980.48.5.862
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Shannon,R
中科院分区：
文献类型：
--
作者：
Shannon,R
为确定肋椎关节手法(CVJM)是否会影响呼吸模式，进行了实验。本实验用双乌拉坦麻醉、迷走神经切断、麻醉和人工呼吸，监测犬的膈神经传出活动(PA)。切断肋骨6-10(双侧)，与肋骨5-11分开。切断胸神经5~11支，仅保留关节神经供应。关节在吸气或呼气方向的手动运动对PA有抑制作用。肋骨的持续移位可抑制PA，持续时间相当于多次呼吸周期。CVJM与PA同步导致呼吸频率增加。在迷走神经切断的自发性呼吸犬中，联合感受器刺激的吸气抑制效应是通过手动按压胸部而引起的，而不是通过人工肺充气或放气。结论：CVJM对呼吸模式的影响是通过刺激关节机械感受器而起作用的，其作用部分是通过延髓-桥脑节律产生器来实现的。
Experiments were conducted to determine if costovertebral joint manipulation (CVJM) could influence the respiratory pattern. Phrenic efferent activity (PA) was monitored in dogs that were anesthetized with Dial-urethane, vagotomized, paralyzed, and artificially ventilated. Ribs 6-10 (bilaterally) were cut and separated from ribs 5-11. Branches of thoracic nerves 5-11 were cut, leaving only the joint nerve supply intact. Manual joint movement in an inspiratory or expiratory direction had an inhibitory effect on PA. Sustained displacement of the ribs could inhibit PA for a duration equal to numerous respiratory cycles. CVJM in synchrony with PA resulted in an increased respiratory rate. The inspiratory inhibitory effect of joint receptor stimulation was elicited with manual chest compression in vagotomized spontaneously breathing dogs, but not with artificial lung inflation or deflation. It is concluded that the effect of CVJM on the respiratory pattern is due to stimulation of joint mechanoreceptors, and that they exert their influence in part via the medullary-pontine rhythm generator.