A STUDY OF ELECTROPHILIC SUBSTITUTION IN PYRROLO[2,3-D]PYRIMIDINE RING
A STUDY OF ELECTROPHILIC SUBSTITUTION IN PYRROLO[2,3-D]PYRIMIDINE RING
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DOI：
10.1002/jhet.5570060211
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发表时间：
1969-01-01
影响因子：
2.4
通讯作者：
TOWNSEND, LB
中科院分区：
文献类型：
--
作者：
GERSTER, JF;HINSHAW, BC;TOWNSEND, LB
Several 4,5‐disubstituted pyrrolo[2,3‐d]pyrimidines were prepared for the first timeviaelectrophilic substitution,e.g.halogenation, nitration and sulfonation. PMR data for certain pyrrolo[2,3‐d]pyrimidines are included which has furnished conclusive evidence that electrophilic substitution occurred at position 5. These pyrrolo[2,3‐d]pyrimidines, with electron ‐withdrawing substituents at position 5, are of considerable interest as bases for the preparation of nucleoside derivatives related to tubercidin, toyocamcin and sangivamycin.
