P-fimbriated Escherichia coli urinary tract infection: a clinical correlation.
P-fimbriated Escherichia coli urinary tract infection: a clinical correlation.
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P-菌毛型大肠杆菌尿路感染：临床相关性。
DOI：
10.1097/00007611-198712000-00012
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发表时间：
1987
影响因子：
1.1
通讯作者：
Kaack,MB
中科院分区：
文献类型：
--
作者：
Dowling,KJ;Roberts,JA;Kaack,MB
我们设计了一项回顾性研究，以确定无症状菌尿、急性尿路综合征、细菌性膀胱炎、急性肾盂肾炎、可能的急性肾盂肾炎以及急性和慢性前列腺炎患者中P-菌毛大肠埃希菌的发生率。此外，我们还比较了未受损宿主与受损宿主、住院患者与门诊患者、儿童与成人之间的发病率。在急性肾盂肾炎或急性前列腺炎的未妥协患者中，超过80%的患者分离到P-菌毛大肠杆菌。在临床上有这些障碍的患者中，发病率下降到大约30%(P<0.05)。025)。年龄和住院/门诊状况都不是显著的影响因素。我们强调，在由大肠杆菌引起的急性肾盂肾炎和急性前列腺炎中，P-菌毛作为毒力因子的重要性，尽管这些疾病可能是由受影响患者的毒力较低的微生物引起的。因此，由P-菌毛阴性的大肠杆菌引起的急性肾盂肾炎或急性前列腺炎的患者可能应该被认为是折衷的；折衷的因素应该被确定作为后续治疗的指导。
We designed a retrospective study to determine the incidence of P-fimbriated Escherichia coli in patients with asymptomatic bacteriuria, acute urethral syndrome, bacterial cystitis, acute pyelonephritis, possible acute pyelonephritis, and acute and chronic prostatitis. In addition, we compared the incidence in uncompromised vs compromised hosts, inpatients vs outpatients, and children vs adults. P-fimbriated E coli were isolated in more than 80% of uncompromised patients with either acute pyelonephritis or acute prostatitis. In clinically compromised patients having these disorders, the incidence dropped to approximately 30%(P less than. 025). Neither age nor inpatient/outpatient status was a significant factor. We stress the importance of P-fimbriation as a virulence factor in acute pyelonephritis and acute prostatitis caused by E coli, though these diseases may be caused by less virulent organisms in compromised patients. Thus, patients with acute pyelonephritis or acute prostatitis caused by E coli negative for P-fimbriae probably should be considered compromised; the compromising factor should be determined as a guide to subsequent treatment.