Bittering agents in the prevention of accidental poisoning: children's reactions to denatonium benzoate (Bitrex).
Bittering agents in the prevention of accidental poisoning: children's reactions to denatonium benzoate (Bitrex).
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苦味剂预防意外中毒：儿童对苯甲酸地那铵（Bitrex）的反应。
DOI：
10.1136/emj.8.1.1
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
N. Frude
中科院分区：
文献类型：
--
作者：
J. Sibert;N. Frude
观察了苯甲酸地那铵（Bitrex）对幼儿的反应，以评估这种苦味剂在预防意外中毒中的潜力。33名17-36个月的儿童被提供含有Bitrex（浓度为百万分之10）的橙子汁。在30名服用这种果汁的儿童中，只有7名愿意服用10克以上。注意到各种负面的口头和非口头反应。这表明，Bitrex的高度不适口性使这种化合物成为一种有用的添加剂，可以很好地防止轻度至中度毒性的家用产品的意外中毒。
The responses of young children to Denatonium Benzoate (Bitrex) were observed, in order to assess the potential of this bittering agent in the prevention of accidental poisoning. Thirty-three children aged 17-36 months were offered orange juice containing Bitrex (in a concentration of 10 parts per million). Of the 30 children who took some of this juice, only seven were willing to take more than 10 gm. A variety of negative verbal and non-verbal responses were noted. It is suggested that the highly unpalatable nature of Bitrex makes this compound a useful additive that could well prevent accidental poisoning from household products of mild to moderate toxicity.