Topological constraints and chromosome organization in eukaryotes: a physical point of view.
Topological constraints and chromosome organization in eukaryotes: a physical point of view.
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真核生物的拓扑约束和染色体组织：物理观点。
DOI：
10.1042/bst20120330
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发表时间：
2013
影响因子：
3.9
通讯作者：
A. Rosa
中科院分区：
文献类型：
--
作者：
A. Rosa
在过去的几年里，新的实验工具能够以前所未有的细节水平探测真核生物基因组的三维组织。在寻求定量的理解实验结果，几个聚合物模型的染色质组织进行了介绍和批判性的评价。在这篇文章中，我给一个简单的介绍染色体组织的物理基础，并回顾实验证据支持的重要性，拓扑结构的限制，在真核生物中的染色体构象的描述。
New experimental tools capable of probing the three-dimensional organization of eukaryotic genomes with an unprecedented level of detail have been developed in the last few years. In the quest for a quantitative understanding of experimental results, several polymer models for chromatin organization were introduced and critically evaluated. In the present article, I give a brief introduction to the physical basis of chromosome organization, and recall the experimental evidence in favour of the importance of topological constraints for the description of chromosome conformations in eukaryotes.
缠结聚合物液体的粘弹性和原始路径分析：从 F-肌动蛋白到聚乙烯
DOI：
--
发表时间：
2008
期刊：
Journal of Chemical Physics 128
影响因子：
--
作者：
Nariya Uchida;Gary. S. Grest;and Ralf Everaers
通讯作者：
and Ralf Everaers