HUMAN CANCER-TREATMENT WITH ULTRASOUND
HUMAN CANCER-TREATMENT WITH ULTRASOUND
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DOI：
10.1109/t-su.1984.31529
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发表时间：
1984-01-01
期刊：
影响因子：
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通讯作者：
KONG, JS
中科院分区：
文献类型：
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作者：
CORRY, PM;JABBOURY, K;KONG, JS
从理论上讲，超声波的治疗应用最早是由Freundlich于1932年提出的[L]，1933年著名生物物理学家阿尔伯特·森特-乔尔吉紧随其后，首次报道了超声波在动物肿瘤中的应用[2]。随着必要的压电技术的进一步发展，Pohlman等人首次发表了用于人体的物理治疗应用。1939年的131年。从那时起，超声波在物理治疗中的应用在世界范围内得到了广泛的普及和持续的增长。第一次描述人类肿瘤的治疗是在1944年，当时Horvath[4]报道了肉瘤的治疗。克雷姆考[S]撰写了一篇对1979年以来超声癌症治疗进展的出色回顾。截至1979年，全世界只有四家机构从事使用超声波治疗人类癌症，美国只有两家[S]。超声波用于癌症治疗的发展相当缓慢，可能是几个因素造成的。首先，来自动物和人体研究的早期报告报告了当超声波被用作单剂治疗时相互矛盾和相当悲观的结果。波尔曼[6]对1950年前的文献进行了调查，结果显示，在报告的133个病例中，只有17%获得了一些益处。这种糟糕的临床表现导致了1949年的“Erlangen决议”，实质上是声明应该放弃在临床癌症治疗中使用超声波。另一个因素与
ISTORICALLY, the therapeutic application of ultrasound was first proposed by Freundlich in 1932 [l], with the first report of its application to an animal tumor following closely in 1933 by the noted biophysicist Albert Szent-Gyorgyi [2]. Further development of the necessary piezoelectric technology led to the first publication of application to humans for the purposes of physical therapy by Pohlman et al. 131 in 1939. Since that time, the application of ultrasound for physical therapy has enjoyed wide popularity and continued growth throughout the world. The first description of the treatment of a human tumor came in 1944 when Horvath [4] reported on the treatment of a sarcoma. An excellent review of progress in ultrasound cancer therapy to 1979 has been written by Kremkau [S]. As of 1979 there were only four institutions engaged in human cancer treatment worldwide using ultrasound, and only two in the United States [S]. The rather slow development of ultrasound for cancer treatment probably resulted from several factors. First, early reports from both animal and human studies reported conflicting and rather pessimistic results when ultrasound was employed as single agent therapy. Pohlman [6] undertook a survey of the literature prior to 1950 and showed that of the 133 cases reported only 17 percent derived some benefit. This poor clinical performance led to the “Erlangen resolution” of 1949 that in essence stated that the use of ultrasound in clinical cancer treatment should be abandoned. Another factor relates to the