Spatial modulation of visual responses arises in cortex with active navigation.
Spatial modulation of visual responses arises in cortex with active navigation.
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视觉反应的空间调制出现在主动导航的大脑皮层。
DOI：
10.7554/elife.63705
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发表时间：
2021-02-04
期刊：
影响因子：
7.7
通讯作者：
Carandini M
中科院分区：
文献类型：
--
作者：
Diamanti EM;Reddy CB;Schröder S;Muzzu T;Harris KD;Saleem AB;Carandini M
在导航过程中，小鼠初级视皮层（V1）神经元的视觉反应受到动物空间位置的调制。在这里，我们表明，这种空间调制同样存在于多个更高的视觉区域，但在主要的丘脑通路到V1可以忽略不计。与海马体类似，视觉皮层的空间调制随着经验和主动行为而加强。因此，在熟悉的环境中主动导航，增强了从皮层开始的视觉信号的空间调制。
During navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but negligible in the main thalamic pathway into V1. Similar to hippocampus, spatial modulation in visual cortex strengthens with experience and with active behavior. Active navigation in a familiar environment, therefore, enhances the spatial modulation of visual signals starting in the cortex.